Risk factors
Risk factors for prostate gland enlargement include:
Race
Family history: Having a blood relative, such as a father or brother, with prostate problems means you're more likely to have problems.
Aging and Dihydrotestosterone (DHT) are the two best-stablished causes required for the developement of BPH. In men castrated prior to puberty, BPH does not develop and regression of BPH and improvement in urinary symptoms has been reported following castration.
Throughout their lives, men produce testosterone, a male hormone, and small amounts of estrogen, a female hormone. As men age, the amount of active testosterone in their blood decreases, which leaves a higher proportion of estrogen. Scientific studies have suggested that benign prostatic hyperplasia may occur because the higher proportion of estrogen within the prostate increases the activity of substances that promote prostate cell growth.
BPH (benign prostatic hyperplasia) is a natural consequence of aging and is more likely to occur in men whose fathers or brothers experienced prostate enlargement.